Stays for 16+ guests in Charleston, SC

• Dunecrest Lane 7

  Cabin · 7 bed · 9 bath · sleeps 18

  Isle of Palms, SC

  From $289 a night

  • balcony
  • cookware
  • deck / patio
  • ice maker

  Exact location

  Book direct on islandrealtyobjective.net

• Six on Cannon

  House · 6 bed · 2 bath · sleeps 16

  Charleston, SC

  From $408 a night

  • body soap
  • pack ’n play/travel crib
  • enhanced cleaning practices
  • town

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Heirloom on Cannon (60.5 A+B)

  House · 6 bed · 6 bath · sleeps 16

  Charleston, SC

  From $411 a night

  • bed linens
  • pack ’n play/travel crib
  • enhanced cleaning practices
  • town

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• The Monroe

  House · 5 bed · 5 bath · sleeps 16

  Charleston, SC

  From $416 a night

  • garden or backyard
  • first aid kit
  • baking sheet
  • luggage dropoff allowed

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Morris Place

  House · 6 bed · 6 bath · sleeps 16

  Charleston, SC

  From $421 a night

  • extra pillows and blankets
  • wine glasses
  • hot water
  • cleaning disinfection

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• The Inns on Spring (90AB)

  House · 8 bed · 6.5 bath · sleeps 18

  Charleston, SC

  From $499 a night

  • conditioner
  • tv
  • garden or backyard
  • dishwasher

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Magnolia House

  House · 6 bed · 3 bath · sleeps 19

  Charleston, SC

  From $695 a night

  • babysitter recommendations
  • long term stays allowed
  • cookware
  • stove

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• French Quarter Estate

  House · 5 bed · 4 bath · sleeps 16

  Charleston, SC

  From $698 a night

  • essentials
  • suitable for children (2-12 years)
  • hot water
  • elevator

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Ivy Manor | Verdana

  Villa · 6 bed · 3.5 bath · sleeps 16

  Charleston, SC

  From $825 a night

  • babysitter recommendations
  • long term stays allowed
  • cookware
  • tv

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• The Manor

  House · 8 bed · 4 bath · sleeps 16

  Charleston, SC

  From $849 a night

  • hair dryer
  • first aid kit
  • baking sheet
  • microwave

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• The Jessamine | Abode

  House · 9 bed · 5.5 bath · sleeps 16

  Charleston, SC

  From $888 a night

  • babysitter recommendations
  • pack ’n play/travel crib
  • dishes and silverware
  • wine glasses

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Silver Spring

  House · 6 bed · 5 bath · sleeps 16

  Charleston, SC

  From $975 a night

  • hangers
  • free parking on street
  • baking sheet
  • oven

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Greystone Manor

  House · 6 bed · 6 bath · sleeps 16

  Charleston, SC

  From $995 a night

  • babysitter recommendations
  • oven
  • dishes and silverware
  • towels provided

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Palmetto Hideaway

  House · 6 bed · 6.5 bath · sleeps 16

  Charleston, SC

  From $1,048 a night

  • conditioner
  • toaster
  • freezer
  • laptop friendly workspace

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• The Ivory

  House · 12 bed · 7.5 bath · sleeps 16

  Charleston, SC

  From $1,097 a night

  • bed linens
  • patio or balcony
  • downtown
  • wireless internet

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Crosstown @ King (92AB)

  House · 8 bed · 8 bath · sleeps 18

  Charleston, SC

  From $1,203 a night

  • babysitter recommendations
  • long term stays allowed
  • fishing
  • cookware

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Crosstown @ King (90AB)

  House · 10 bed · 10 bath · sleeps 22

  Charleston, SC

  From $1,500 a night

  • essentials
  • washer
  • high touch surfaces disinfected
  • outdoor seating (furniture)

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• 1 Nicklaus Lane

  Villa · 7 bed · 7 bath · sleeps 16

  Kiawah Island, SC

  From $1,137 a night

  • the 100 collection™
  • long-term stays
  • satellite or cable tv
  • television(s)

  Exact location

  Book direct on South Carolina's Premier Real Estate and Vacation Rental Company

• Sea Gem

  House · 7 bed · 1 bath · sleeps 19

  Isle of Palms, SC

  From $730 a night

  • king bed
  • seating area
  • mounted smart tv

  Exact location

  Book direct on iTrip

• 1006 Carolina Blvd - Sea Glass

  House · 8 bed · 7 bath · sleeps 18

  Isle of Palms, SC

  From $771 a night

  • children welcome
  • infants welcome
  • smoking not allowed
  • wheelchair inaccessible

  Exact location

  Book direct on Isle of Palms Rentals, IOP Escapes Vacation Rentals

• 8 Bedrooms - Full QuadPlex - 10 min. to Downtown

  Apartment · 8 bed · 4 bath · sleeps 16

  North Charleston

  From $258 a night

  Exact location

  Book direct on The Boroughs

• Lake Palmetto DBL - 2 Spacious homes on the Lake!

  Apartment · 7 bed · 7 bath · sleeps 16

  North Charleston

  From $299 a night

  Exact location

  Book direct on The Boroughs

• 8 Bedroom - Close to King Street - with Parking!

  House · 8 bed · 4 bath · sleeps 16

  Charleston

  From $318 a night

  Exact location

  Book direct on The Boroughs

• 8BR - Beautiful CHS Home | Great for Groups

  House · 8 bed · 4 bath · sleeps 16

  Charleston

  From $395 a night

  Exact location

  Book direct on The Boroughs

• Charleston Style Full Duplex -2 Blocks to King St

  House · 6 bed · 4 bath · sleeps 16

  Charleston

  From $400 a night

  Exact location

  Book direct on The Boroughs

• 8 Bedroom - Newly Renovated - Parking & Walkable

  Apartment · 8 bed · 6 bath · sleeps 16

  Charleston

  From $449 a night

  Exact location

  Book direct on The Boroughs

• 8BR-Spring Street Retreat ~ 2 Full Homes Together

  House · 8 bed · 6 bath · sleeps 16

  Charleston

  From $449 a night

  Exact location

  Book direct on The Boroughs

• Downtown Duplex - Coming St

  Apartment · 6 bed · 4 bath · sleeps 16

  Charleston

  From $495 a night

  Exact location

  Book direct on The Boroughs

• Downtown Duplex - St Philip St

  House · 6 bed · 5 bath · sleeps 16

  Charleston

  From $595 a night

  Exact location

  Book direct on The Boroughs

• The Boroughs on Folly - Sleeps 20+

  Apartment · 8 bed · 4 bath · sleeps 20

  Folly Beach

  From $633 a night

  Exact location

  Book direct on The Boroughs

• Bridge View Double - Two Luxury Homes - Sleeps 16

  House · 6 bed · 8 bath · sleeps 16

  Mount Pleasant

  From $690 a night

  Exact location

  Book direct on The Boroughs

• Barbara Street Double - Two Houses Side by Side

  House · 7 bed · 5 bath · sleeps 16

  Mount Pleasant

  From $832 a night

  Exact location

  Book direct on The Boroughs

• Carolina Blvd 1002

  Cabin · 8 bed · 8 bath · sleeps 18

  Isle of Palms, SC

  No nightly rate published

  • cookware
  • ice maker
  • laundry room
  • linens provided

  Exact location

  Book direct on islandrealtyobjective.net

• Palm Blvd 2203

  Cabin · 6 bed · 6 bath · sleeps 16

  Isle of Palms, SC

  No nightly rate published

  • cookware
  • deck / patio
  • ice maker
  • laundry room

  Exact location

  Book direct on islandrealtyobjective.net

• Blue Magnolia

  House · 7 bed · 4 bath · sleeps 17

  Charleston, SC

  No nightly rate published

  • heating
  • emergency exit
  • blender
  • pack ’n play/travel crib

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Chateu Charleston

  House · 4 bed · 4.5 bath · sleeps 16

  Charleston, SC

  No nightly rate published

  • baking sheet
  • oven
  • dishes and silverware
  • towels provided

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Fire Tower

  Condo · 12 bed · 6.5 bath · sleeps 30

  Charleston, SC

  No nightly rate published

  • cookware
  • towels provided
  • hangers
  • dishwasher

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Heirloom South | Residence

  House · 9 bed · 8.5 bath · sleeps 16

  Charleston, SC

  No nightly rate published

  • cookware
  • dishwasher
  • hot water
  • babysitter recommendations

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Heirloom Spring (ABCD)

  House · 9 bed · 6 bath · sleeps 16

  Charleston, SC

  No nightly rate published

  • extra pillows and blankets
  • bathtub
  • iron
  • cleaning disinfection

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Heirloom Spring | Full Compound

  House · 18 bed · 14.5 bath · sleeps 30

  Charleston, SC

  No nightly rate published

  • conditioner
  • tv
  • freezer
  • first aid kit

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Heirloom on Cannon (60 A+B)

  House · 10 bed · 7 bath · sleeps 26

  Charleston, SC

  No nightly rate published

  • babysitter recommendations
  • microwave
  • dishes and silverware
  • toaster

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Ivy Manor

  House · 8 bed · 4.5 bath · sleeps 16

  Charleston, SC

  No nightly rate published

  • babysitter recommendations
  • microwave
  • cookware
  • toaster

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Modera House

  House · 6 bed · 6 bath · sleeps 16

  Charleston, SC

  No nightly rate published

  • family/kid friendly
  • bathtub
  • iron
  • cleaning disinfection

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• Rutledge House

  House · 8 bed · 8 bath · sleeps 18

  Charleston, SC

  No nightly rate published

  • babysitter recommendations
  • microwave
  • cookware
  • toaster

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• The Chapel

  House · 13 bed · 12.5 bath · sleeps 16

  Charleston, SC

  No nightly rate published

  • babysitter recommendations
  • luggage dropoff allowed
  • cookware
  • tv

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• The Chapel | Grand

  House · 8 bed · 8 bath · sleeps 16

  Charleston, SC

  No nightly rate published

  • hair dryer
  • laptop friendly workspace
  • air conditioning
  • microwave

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• The Grand Estate

  House · 11 bed · 8 bath · sleeps 24

  Charleston, SC

  No nightly rate published

  • heating
  • washer
  • bed linens
  • iron

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• The Line Loft | Overlook

  Loft · 7 bed · 6 bath · sleeps 16

  Charleston, SC

  No nightly rate published

  • freezer
  • first aid kit
  • air conditioning
  • luggage dropoff allowed

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• The OakTree

  House · 7 bed · 7.5 bath · sleeps 16

  Charleston, SC

  No nightly rate published

  • heating
  • outdoor seating (furniture)
  • blender
  • pack ’n play/travel crib

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• The Rose

  House · 6 bed · 4 bath · sleeps 16

  Charleston, SC

  No nightly rate published

  • hangers
  • dining table
  • blender
  • oven

  Exact location

  Book direct on Top Vacation Rental in the Lowcountry

• 46 Surfsong Road

  Villa · 7 bed · 8 bath · sleeps 16

  Kiawah Island, SC

  No nightly rate published

  • the 100 collection™
  • long-term stays
  • pool table
  • satellite or cable tv

  Exact location

  Book direct on South Carolina's Premier Real Estate and Vacation Rental Company

• The%20Juliette-Entire%20Luxury%20Residence

  House · 6 bed · 4 bath · sleeps 16

  Charleston

  No nightly rate published

  • parking
  • parking%20on%20street
  • beach%20chairs

  Exact location

  Book direct on The Betz Team / Home

• Downtown Charleston Home + Private Pool and Garden

  House · 6 bed · 6 bath · sleeps 16

  Charleston, SC

  No nightly rate published

  Exact location

  Book direct on Luxury Vacation Rentals and Vacation Homes by Wander

• Downtown Duplex - Spring St

  House · 8 bed · 8 bath · sleeps 26

  Charleston

  No nightly rate published

  Exact location

  Book direct on The Boroughs

• The Arbor Spring Court Complex

  House · 12 bed · 12 bath · sleeps 16

  Charleston

  No nightly rate published

  Exact location

  Book direct on https://www.instagram.com/charlestonvacays/

• The Cannon Exchange Building | Two Luxury Residences | 1 Block to King Street

  Apartment · 10 bed · 10 bath · sleeps 28

  Charleston

  No nightly rate published

  Exact location

  Book direct on https://www.instagram.com/charlestonvacays/

• The Dahlia & Florian Estate — Ultimate Designer 7BR Compound with Private Heated Pool & Parking

  Apartment · 7 bed · 5 bath · sleeps 18

  Charleston

  No nightly rate published

  Exact location

  Book direct on The Cannonborough Grand

• The Edisto Complex- 8 Bedroom/ 8 Bathroom- 4 Condo Complex- 122 Complex

  Condo · 8 bed · 8 bath · sleeps 24

  Charleston

  No nightly rate published

  Exact location

  Book direct on https://www.instagram.com/charlestonvacays/

• The Madison Compound Historic House & Suites

  House · 6 bed · 7 bath · sleeps 16

  Charleston

  No nightly rate published

  Exact location

  Book direct on https://www.instagram.com/charlestonvacays/

• The Madison Compound Historic House & Suites

  House · 6 bed · 7 bath · sleeps 16

  Charleston

  No nightly rate published

  Exact location

  Book direct on Charleston Vacays

These are the cheapest; there are more. Narrow by facet above, or ask an agent through https://otaless.com/mcp.

How prices are computed

Lowest rate the manager has published. Your dates may cost more; the real price is on their site. The "from" figure is the lowest nightly rate the manager published on that listing page when we last fetched it. It excludes taxes, cleaning and other fees, it is not a quote, and it is not live availability.

Updated 2026-10-29 19:18 UTC. Prices and facts are whatever the manager published on their own site.