Houses for 16+ guests in Charleston, SC
Houses for 16+ guests in Charleston, SC, from $318 a night. Book direct on each manager's site, no OTA fee.
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Six on Cannon
House · 6 bed · 2 bath · sleeps 16
Charleston, SC
From $408 a night
- garden or backyard
- ceiling fan
- baking sheet
- luggage dropoff allowed
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Heirloom on Cannon (60.5 A+B)
House · 6 bed · 6 bath · sleeps 16
Charleston, SC
From $411 a night
- high chair
- outdoor kitchen
- blender
- patio or balcony
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Monroe
House · 5 bed · 5 bath · sleeps 16
Charleston, SC
From $416 a night
- coffee
- safe
- fire extinguisher
- suitable for children (2-12 years)
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Morris Place
House · 6 bed · 6 bath · sleeps 16
Charleston, SC
From $421 a night
- heating
- dishwasher
- blender
- pack ’n play/travel crib
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Inns on Spring (90AB)
House · 8 bed · 6.5 bath · sleeps 18
Charleston, SC
From $499 a night
- babysitter recommendations
- luggage dropoff allowed
- cookware
- toaster
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Magnolia House
House · 6 bed · 3 bath · sleeps 19
Charleston, SC
From $695 a night
- body soap
- pack ’n play/travel crib
- enhanced cleaning practices
- town
Exact location
Book direct on Top Vacation Rental in the Lowcountry
French Quarter Estate
House · 5 bed · 4 bath · sleeps 16
Charleston, SC
From $698 a night
- dryer
- wine glasses
- high chair
- cable tv
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Manor
House · 8 bed · 4 bath · sleeps 16
Charleston, SC
From $849 a night
- dishes and silverware
- toaster
- hangers
- laptop friendly workspace
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Jessamine | Abode
House · 9 bed · 5.5 bath · sleeps 16
Charleston, SC
From $888 a night
- babysitter recommendations
- pack ’n play/travel crib
- dishes and silverware
- wine glasses
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Silver Spring
House · 6 bed · 5 bath · sleeps 16
Charleston, SC
From $975 a night
- babysitter recommendations
- microwave
- dishes and silverware
- tv
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Greystone Manor
House · 6 bed · 6 bath · sleeps 16
Charleston, SC
From $995 a night
- family/kid friendly
- suitable for children (2-12 years)
- iron
- cleaning disinfection
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Palmetto Hideaway
House · 6 bed · 6.5 bath · sleeps 16
Charleston, SC
From $1,048 a night
- essentials
- suitable for children (2-12 years)
- internet
- mini fridge
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Ivory
House · 12 bed · 7.5 bath · sleeps 16
Charleston, SC
From $1,097 a night
- hangers
- dishwasher
- baking sheet
- pack ’n play/travel crib
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Crosstown @ King (92AB)
House · 8 bed · 8 bath · sleeps 18
Charleston, SC
From $1,203 a night
- babysitter recommendations
- long term stays allowed
- fishing
- cookware
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Crosstown @ King (90AB)
House · 10 bed · 10 bath · sleeps 22
Charleston, SC
From $1,500 a night
- essentials
- washer
- high touch surfaces disinfected
- outdoor seating (furniture)
Exact location
Book direct on Top Vacation Rental in the Lowcountry
1006 Carolina Blvd - Sea Glass
House · 8 bed · 7 bath · sleeps 18
Isle of Palms, SC
From $732 a night
- children welcome
- infants welcome
- smoking not allowed
- wheelchair inaccessible
Exact location
Book direct on Isle of Palms Rentals, IOP Escapes Vacation Rentals
8 Bedroom - Close to King Street - with Parking!
House · 8 bed · 4 bath · sleeps 16
Charleston
From $318 a night
Exact location
Book direct on The Boroughs
8BR - Beautiful CHS Home | Great for Groups
House · 8 bed · 4 bath · sleeps 16
Charleston
From $395 a night
Exact location
Book direct on The Boroughs
Charleston Style Full Duplex -2 Blocks to King St
House · 6 bed · 4 bath · sleeps 16
Charleston
From $400 a night
Exact location
Book direct on The Boroughs
8BR-Spring Street Retreat ~ 2 Full Homes Together
House · 8 bed · 6 bath · sleeps 16
Charleston
From $449 a night
Exact location
Book direct on The Boroughs
Downtown Duplex - St Philip St
House · 6 bed · 5 bath · sleeps 16
Charleston
From $595 a night
Exact location
Book direct on The Boroughs
Bridge View Double - Two Luxury Homes - Sleeps 16
House · 6 bed · 8 bath · sleeps 16
Mount Pleasant
From $690 a night
Exact location
Book direct on The Boroughs
Barbara Street Double - Two Houses Side by Side
House · 7 bed · 5 bath · sleeps 16
Mount Pleasant
From $832 a night
Exact location
Book direct on The Boroughs
Blue Magnolia
House · 7 bed · 4 bath · sleeps 17
Charleston, SC
No nightly rate published
- heating
- emergency exit
- blender
- pack ’n play/travel crib
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Chateu Charleston
House · 4 bed · 4.5 bath · sleeps 16
Charleston, SC
No nightly rate published
- hangers
- dining table
- bed linens
- pack ’n play/travel crib
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Heirloom South | Residence
House · 9 bed · 8.5 bath · sleeps 16
Charleston, SC
No nightly rate published
- cookware
- dishwasher
- hot water
- babysitter recommendations
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Heirloom Spring (ABCD)
House · 9 bed · 6 bath · sleeps 16
Charleston, SC
No nightly rate published
- high touch surfaces disinfected
- sauna
- blender
- private entrance
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Heirloom Spring | Full Compound
House · 18 bed · 14.5 bath · sleeps 30
Charleston, SC
No nightly rate published
- conditioner
- tv
- freezer
- first aid kit
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Heirloom on Cannon (60 A+B)
House · 10 bed · 7 bath · sleeps 26
Charleston, SC
No nightly rate published
- hangers
- outdoor seating (furniture)
- baking sheet
- oven
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Ivy Manor
House · 8 bed · 4.5 bath · sleeps 16
Charleston, SC
No nightly rate published
- bed linens
- pack ’n play/travel crib
- downtown
- town
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Modera House
House · 6 bed · 6 bath · sleeps 16
Charleston, SC
No nightly rate published
- essentials
- suitable for children (2-12 years)
- hot water
- body soap
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Rutledge House
House · 8 bed · 8 bath · sleeps 18
Charleston, SC
No nightly rate published
- dishes and silverware
- towels provided
- heating
- dishwasher
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Chapel
House · 13 bed · 12.5 bath · sleeps 16
Charleston, SC
No nightly rate published
- babysitter recommendations
- luggage dropoff allowed
- cookware
- tv
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Chapel | Grand
House · 8 bed · 8 bath · sleeps 16
Charleston, SC
No nightly rate published
- babysitter recommendations
- oven
- downtown
- town
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Grand Estate
House · 11 bed · 8 bath · sleeps 24
Charleston, SC
No nightly rate published
- heating
- washer
- bed linens
- iron
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The OakTree
House · 7 bed · 7.5 bath · sleeps 16
Charleston, SC
No nightly rate published
- heating
- outdoor seating (furniture)
- blender
- pack ’n play/travel crib
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Rose
House · 6 bed · 4 bath · sleeps 16
Charleston, SC
No nightly rate published
- hangers
- dining table
- blender
- oven
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The%20Juliette-Entire%20Luxury%20Residence
House · 6 bed · 4 bath · sleeps 16
Charleston
No nightly rate published
- parking
- parking%20on%20street
- beach%20chairs
Exact location
Book direct on The Betz Team / Home
Downtown Charleston Home + Private Pool and Garden
House · 6 bed · 6 bath · sleeps 16
Charleston, SC
No nightly rate published
Exact location
Book direct on Luxury Vacation Rentals and Vacation Homes by Wander
Downtown Duplex - Spring St
House · 8 bed · 8 bath · sleeps 26
Charleston
No nightly rate published
Exact location
Book direct on The Boroughs
Sunset Marsh Estate//Horizon pool/ Gourmet kitchen
House · 8 bed · 8 bath · sleeps 18
Johns Island, SC
No nightly rate published
Exact location
Book direct on Luxury Vacation Rentals and Vacation Homes by Wander
The Arbor Spring Court Complex
House · 12 bed · 12 bath · sleeps 16
Charleston
No nightly rate published
Exact location
Book direct on https://www.instagram.com/charlestonvacays/
The Madison Compound Historic House & Suites
House · 6 bed · 7 bath · sleeps 16
Charleston
No nightly rate published
Exact location
Book direct on https://www.instagram.com/charlestonvacays/
The Madison Compound Historic House & Suites
House · 6 bed · 7 bath · sleeps 16
Charleston
No nightly rate published
Exact location
Book direct on Charleston Vacays
Waterfront Retreat, 2 Homes, 10Min- DT & Beach
House · 8 bed · 7 bath · sleeps 23
North Charleston, SC
No nightly rate published
Exact location
Book direct on Luxury Vacation Rentals and Vacation Homes by Wander
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How prices are computed
Lowest rate the manager has published. Your dates may cost more; the real price is on their site. The "from" figure is the lowest nightly rate the manager published on that listing page when we last fetched it. It excludes taxes, cleaning and other fees, it is not a quote, and it is not live availability.
Updated 2026-10-31 06:56 UTC. Prices and facts are whatever the manager published on their own site.