Houses for 12+ guests in Charleston, SC
Houses for 12+ guests in Charleston, SC, from $184 a night. Book direct on each manager's site, no OTA fee.
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Chateau Charleston | Charmer
House · 4 bed · 3 bath · sleeps 12
Charleston, SC
From $294 a night
- hair dryer
- first aid kit
- baking sheet
- microwave
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Brick & Mortar
House · 4 bed · 2 bath · sleeps 12
Charleston, SC
From $395 a night
- babysitter recommendations
- microwave
- cookware
- toaster
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Peach Tree House
House · 4 bed · 2 bath · sleeps 12
Charleston, SC
From $395 a night
- oven
- blender
- wine glasses
- freezer
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Six on Cannon
House · 6 bed · 2 bath · sleeps 16
Charleston, SC
From $408 a night
- body soap
- pack ’n play/travel crib
- enhanced cleaning practices
- town
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Heirloom on Cannon (60.5 A+B)
House · 6 bed · 6 bath · sleeps 16
Charleston, SC
From $411 a night
- bed linens
- pack ’n play/travel crib
- enhanced cleaning practices
- town
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Monroe
House · 5 bed · 5 bath · sleeps 16
Charleston, SC
From $416 a night
- garden or backyard
- first aid kit
- baking sheet
- luggage dropoff allowed
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Morris Place
House · 6 bed · 6 bath · sleeps 16
Charleston, SC
From $421 a night
- extra pillows and blankets
- wine glasses
- hot water
- cleaning disinfection
Exact location
Book direct on Top Vacation Rental in the Lowcountry
High Society
House · 6 bed · 4 bath · sleeps 12
Charleston, SC
From $422 a night
- babysitter recommendations
- long term stays allowed
- cookware
- stove
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Elliotborough Suite
House · 4 bed · 4.5 bath · sleeps 12
Charleston, SC
From $450 a night
- high chair
- dining table
- blender
- private entrance
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Harbor Mist House
House · 4 bed · 3.5 bath · sleeps 14
Charleston, SC
From $455 a night
- babysitter recommendations
- oven
- dishes and silverware
- towels provided
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Saint Charmer
House · 6 bed · 5.5 bath · sleeps 12
Charleston, SC
From $495 a night
- body soap
- first aid kit
- hangers
- private entrance
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Islander House
House · 3 bed · 3.5 bath · sleeps 12
Charleston, SC
From $498 a night
- heating
- outdoor seating (furniture)
- blender
- pack ’n play/travel crib
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Inns on Spring (90AB)
House · 8 bed · 6.5 bath · sleeps 18
Charleston, SC
From $499 a night
- conditioner
- tv
- garden or backyard
- dishwasher
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Charlee Rowhouse
House · 5 bed · 4 bath · sleeps 12
Charleston, SC
From $500 a night
- body soap
- private entrance
- essentials
- wireless internet
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Funky Folly
House · 5 bed · 4 bath · sleeps 12
Folly Beach, SC
From $595 a night
- conditioner
- towels provided
- hair dryer
- dishwasher
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Charleston Abode
House · 6 bed · 4 bath · sleeps 14
Charleston, SC
From $597 a night
- conditioner
- stove
- freezer
- first aid kit
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Crosstown @ King (86AB)
House · 6 bed · 4 bath · sleeps 14
Charleston, SC
From $600 a night
- conditioner
- smoke detector
- freezer
- pets allowed
Exact location
Book direct on Top Vacation Rental in the Lowcountry
French Quarter Suite
House · 4 bed · 3 bath · sleeps 14
Charleston, SC
From $695 a night
- hair dryer
- dining table
- baking sheet
- microwave
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Magnolia House
House · 6 bed · 3 bath · sleeps 19
Charleston, SC
From $695 a night
- babysitter recommendations
- long term stays allowed
- cookware
- stove
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Chapel | Estate
House · 5 bed · 4.5 bath · sleeps 12
Charleston, SC
From $695 a night
- heating
- dishwasher
- blender
- pack ’n play/travel crib
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Skyline
House · 5 bed · 4.5 bath · sleeps 12
Charleston, SC
From $695 a night
- conditioner
- tv
- hair dryer
- first aid kit
Exact location
Book direct on Top Vacation Rental in the Lowcountry
French Quarter Estate
House · 5 bed · 4 bath · sleeps 16
Charleston, SC
From $698 a night
- essentials
- suitable for children (2-12 years)
- hot water
- elevator
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Quaint
House · 5 bed · 6 bath · sleeps 12
Charleston, SC
From $722 a night
- shampoo
- body soap
- bathtub
- extra pillows and blankets
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Manor
House · 8 bed · 4 bath · sleeps 16
Charleston, SC
From $849 a night
- hair dryer
- first aid kit
- baking sheet
- microwave
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Golden Hour
House · 6 bed · 4 bath · sleeps 14
Charleston, SC
From $850 a night
- bed linens
- oven
- dryer
- towels provided
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Crosstown @ King (94AB)
House · 6 bed · 6 bath · sleeps 14
Charleston, SC
From $853 a night
- body soap
- patio or balcony
- outdoor pool
- enhanced cleaning practices
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Jessamine | Abode
House · 9 bed · 5.5 bath · sleeps 16
Charleston, SC
From $888 a night
- babysitter recommendations
- pack ’n play/travel crib
- dishes and silverware
- wine glasses
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Silver Spring
House · 6 bed · 5 bath · sleeps 16
Charleston, SC
From $975 a night
- hangers
- free parking on street
- baking sheet
- oven
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Greystone Manor
House · 6 bed · 6 bath · sleeps 16
Charleston, SC
From $995 a night
- babysitter recommendations
- oven
- dishes and silverware
- towels provided
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Palmetto Hideaway
House · 6 bed · 6.5 bath · sleeps 16
Charleston, SC
From $1,048 a night
- conditioner
- toaster
- freezer
- laptop friendly workspace
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Crosstown @ King (90A)
House · 5 bed · 5 bath · sleeps 12
Charleston, SC
From $1,075 a night
- pack ’n play/travel crib
- ice maker
- body soap
- town
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Ivory
House · 12 bed · 7.5 bath · sleeps 16
Charleston, SC
From $1,097 a night
- bed linens
- patio or balcony
- downtown
- wireless internet
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Emerson Square
House · 5 bed · 4 bath · sleeps 15
Charleston, SC
From $1,180 a night
- bed linens
- dishwasher
- heating
- tv
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Crosstown @ King (92AB)
House · 8 bed · 8 bath · sleeps 18
Charleston, SC
From $1,203 a night
- babysitter recommendations
- long term stays allowed
- fishing
- cookware
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Crosstown @ King (90AB)
House · 10 bed · 10 bath · sleeps 22
Charleston, SC
From $1,500 a night
- essentials
- washer
- high touch surfaces disinfected
- outdoor seating (furniture)
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Morris Manor
House · 6 bed · 6 bath · sleeps 12
Charleston, SC
From $1,500 a night
- babysitter recommendations
- luggage dropoff allowed
- cookware
- tv
Exact location
Book direct on Top Vacation Rental in the Lowcountry
The Charlee Rowhouse
House · 4 bed · 4 bath · sleeps 14
Charleston, SC
From $500 a night
- heating
- outdoor seating (furniture)
- blender
- pack ’n play/travel crib
Exact location
Book direct on Top Vacation Rental in the Lowcountry
Luxury, Dog-Friendly, Oceanfront Home on Folly Beach
House · 5 bed · 5.5 bath · sleeps 12
Folly Beach, SC
From $597 a night
- air conditioning
- bbq grill
- bathtub
- beach
Exact location
Book direct on CielStay
3407 Palm Blvd. - Beach Retreat
House · 5 bed · sleeps 12
Isle of Palms, SC
From $719 a night
- children welcome
- infants welcome
- smoking not allowed
- wheelchair accessible
Exact location
Book direct on Isle of Palms Rentals, IOP Escapes Vacation Rentals
1006 Carolina Blvd - Sea Glass
House · 8 bed · 7 bath · sleeps 18
Isle of Palms, SC
From $771 a night
- children welcome
- infants welcome
- smoking not allowed
- wheelchair inaccessible
Exact location
Book direct on Isle of Palms Rentals, IOP Escapes Vacation Rentals
914 Carolina Blvd - Twin Palms
House · 7 bed · 5 bath · sleeps 12
Isle of Palms, SC
From $795 a night
- children welcome
- infants welcome
- smoking not allowed
- wheelchair inaccessible
Exact location
Book direct on Isle of Palms Rentals, IOP Escapes Vacation Rentals
Heaven on Earth
House · 5 bed · 1 bath · sleeps 12
Isle of Palms, SC
From $1,492 a night
- closet
- dresser with smart tv
- seating area
- private pool and private hot tub
Exact location
Book direct on iTrip
Sand Wedge by AvantStay | Right on the Golf Course
House · 4 bed · 4 bath · sleeps 12
Isle Of Palms, SC
From $636 a night
- air conditioning
- available in the house: free wifi
- balcony
- barbecue grill
City-level location
Book direct on Book Vacation Rentals, Holiday Rental Homes Directly From Owners
Palm Warbler
House · 5 bed · 1 bath · sleeps 12
Kiawah Island, SC
From $184 a night
Exact location
Book direct on iTrip
1827 OB - Full Compound
House · 6 bed · 4 bath · sleeps 14
North Charleston
From $214 a night
Exact location
Book direct on The Boroughs
Whale of a Time
House · 5 bed · 1 bath · sleeps 12
Isle of Palms, SC
From $214 a night
Exact location
Book direct on iTrip
4 Bedroom - 2 Blocks to King Street!
House · 4 bed · 2 bath · sleeps 12
Charleston
From $216 a night
Exact location
Book direct on The Boroughs
Sparkling Sea
House · 5 bed · 1 bath · sleeps 12
Isle of Palms, SC
From $231 a night
Exact location
Book direct on iTrip
The Queen on King Street 7 Bedroom Duplex
House · 7 bed · 4 bath · sleeps 14
Charleston
From $256 a night
Exact location
Book direct on The Boroughs
Pool Oasis! - 4 Bedrooms - Close to Downtown
House · 4 bed · 3 bath · sleeps 12
North Charleston
From $295 a night
Exact location
Book direct on The Boroughs
8 Bedroom - Close to King Street - with Parking!
House · 8 bed · 4 bath · sleeps 16
Charleston
From $318 a night
Exact location
Book direct on The Boroughs
Folly Beach Compound - Near the Beach & Center St!
House · 4 bed · 3 bath · sleeps 12
Folly Beach
From $348 a night
Exact location
Book direct on The Boroughs
Sun, Sea and Stars
House · 5 bed · 1 bath · sleeps 12
Isle of Palms, SC
From $361 a night
Exact location
Book direct on iTrip
Sea Gem Too
House · 5 bed · 1 bath · sleeps 12
Isle of Palms, SC
From $394 a night
Exact location
Book direct on iTrip
8BR - Beautiful CHS Home | Great for Groups
House · 8 bed · 4 bath · sleeps 16
Charleston
From $395 a night
Exact location
Book direct on The Boroughs
Charleston Style Full Duplex -2 Blocks to King St
House · 6 bed · 4 bath · sleeps 16
Charleston
From $400 a night
Exact location
Book direct on The Boroughs
7 BR Triplex - Newly Renovated! Close to Downtown
House · 7 bed · 4 bath · sleeps 14
North Charleston
From $414 a night
Exact location
Book direct on The Boroughs
These are the cheapest; there are more. Narrow by facet above, or ask an agent through https://otaless.com/mcp.
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How prices are computed
Lowest rate the manager has published. Your dates may cost more; the real price is on their site. The "from" figure is the lowest nightly rate the manager published on that listing page when we last fetched it. It excludes taxes, cleaning and other fees, it is not a quote, and it is not live availability.
Updated 2026-10-30 05:35 UTC. Prices and facts are whatever the manager published on their own site.